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TARGETED CELLULAR NUTRITION
A new class of nutrition
Our goal is not to stop aging—we’re continuously looking for ways to optimize cellular health regardless of age. Following a decade of uncompromising research, clinical trials, and scientific achievements with the Swiss Federal Institute of Technology Lausanne, we’re now launching a new class of nutrition that can help address age-associated cellular decline by revitalizing mitochondria and powering muscle cells.
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HOW AGING IMPACTS CELLS
Cells change as we age
The trillions of cells that comprise our body tissues run on the energy created by our mitochondria—about 90% of our energy comes from these power houses. As we age, the mitochondria break down and lose their efficiency, which can have an effect on our performance. Age-associated cellular decline not only includes a progressive decline in muscle function, but also in our metabolism, our overall energy levels, and resiliency.
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THE POWER HOUSE OF THE CELL
Mitophagy is the key
Over time, the mitochondria in our cells become less efficient in generating energy, resulting in a decline in our cellular health. Our cells can protect themselves from this through a process known as mitophagy— a potent recycling and cleansing mechanism. This process cleans up defective mitochondria and allows the mitochondria to repair itself and improve its performance. We can’t just depend on our bodies’ natural ability to activate mitophagy; it slows down as we age.
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Mitopure has been tested in human clinical trials and has been shown to revitalize mitochrondria and boost muscle function.*
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NOVEL CELLULAR NUTRIENT
Mitopure in your diet
When we eat food—like pomegranates—that are rich in compounds called ellagitannins, these compounds can be transformed into Urolithin A. Urolithin A stimulates mitophagy. But only 30%-40% of people have the right gut bacteria to produce it. Even in that small group that can produce it, it takes a complex set of circumstances, starting by eating the right foods, like pomegranates, select berries, and nuts. And then it would be guesswork as to how much Urolithin A you are creating.
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CLINICALLY PROVEN**
Mitopure delivers 6x more**
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SCIENTIFIC AND CLINICAL ADVISORS
Science and Medicine
The findings behind Timeline started with a team of PhDs and MDs, rigorously searching for a new way to deliver nutrition at the cellular level. As a result of their diligence, Mitopure (proprietary Urolithin A) has been favorably reviewed by the FDA as generally recognized as safe (GRAS) and the biology and clinical science of Mitopure has been published in leading peer reviewed scientific journals such as Nature Medicine and Nature Metabolism.
Timeline is a brand of Amazentis: an innovative life science company based in Switzerland. Amazentis’ advisory board includes world class scientists and medical professionals.
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Patrick Aebischer, MD
Chairman of the Scientific Advisory Board
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President Emeritus of the Swiss Federal Technology Institute
EPFL, Lausanne, Switzerland
Neurodegenerative diseases
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Johan Auwerx, MD, PhD
Member of the Scientific Advisory Board
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Professor at the EPFL, Lausanne, Switzerland
Energy metabolism and mitochondrial function
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Carmen Sandi, PhD
Member of the Scientific Advisory Board
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Director, Brain and Mind Institute
Professor at the EPFL, Lausanne, Switzerland
Neurobehavioral science and stress related brain disorders
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Navindra Seeram, PhD
Member of the Scientific Advisory Board
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Professor and Chairperson Department of
Biomedical and Pharmaceutical Sciences, University of Rhode Island, USA
Natural products discovery
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Michel Aguet, MD
Member of the Scientific Advisory Board
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Professor Emeritus, EPFL, Lausanne Switzerland
Former Director of the Swiss Institute for Experimental Cancer Research (ISREC)
Cancer biology, molecular biology, stem cells and drug target validation
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Roger Fielding, PhD
Clinical Advisor
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Director and Senior Scientist of Nutrition
Exercise Physiology and Sarcopenia Laboratory, Tufts University
Exercise physiology, nutrition, sarcopenia
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Stuart Phillips, PhD
Clinical Advisor
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Director, Physical Activity Centre of Excellence (PACE)
Director, Centre for Nutrition, Exercise, and Health Research, McMaster University
Skeletal muscle health and exercise physiology
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Jeremy D. Walston, MD
Clinical Advisor
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Professor of Geriatric Medicine and Gerontology
Johns Hopkins University School of Medicine
Geriatric medicine, chronic inflammation and mitochondrial biology, frailty research
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ESSENTIAL READING
