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Undoing Aging conference: key take aways for 2019

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The event took place in Berlin in May this year. The city wasn’t a random choice, as Berlin is said to be home to an inspiring concentration of innovative start-up companies that are focused on revolutionizing smart nutrition and healthy food.

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As a scientist at Amazentis, I was there to present the data on the anti-aging effects of Urolithin A, a natural compound produced by the gut microflora upon ingestion of elements that are abundant in pomegranates as well as some types of nuts and berries.

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Mitopure was orally administered in both single and multiple (4 weeks) daily dosing to 60 healthy elderly subjects in a double-blind, randomized, placebo-controlled study. The trial showed that regular Mitopure dosing during 4 weeks is safe, bioavailable, and effective in improving mitochondrial health.

People were excited about the research and the clinical data on Mitopure (presented pre-publication at the time of the Undoing Aging event).

On the other hand, I was inspired to see and interact with so many people interested in advancing the field of longevity. I noticed more than just scientists or venture capitalists. I saw curious people from diverse walks of life who wanted to learn more about aging. They wanted to discover everything from new strategies that slow down aging to how to improve age-related muscle decline. On a more personal level, they wanted to know what to give their family members to make them feel better.

Many people came to ask questions on Urolithin A. Here are the two most frequent ones.

Is Urolithin A safe?

Yes, it is. The first-in-human clinical trial showed that Urolithin A is safe, bioavailable, and has beneficial effects on the health of mitochondria in human skeletal muscle.

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These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease. References: *Nutrition studies: 500mg Mitopure® have been shown to (1) induce gene expression related to mitochondria function and metabolism and (2) increase the strength of the hamstring leg muscle in measures of knee extension and flexion in overweight 40-65 year olds. Data from two randomized double-blind placebo-controlled human clinical trials. **Nutrition NOURISH Study: 500mg Mitopure® have been shown to deliver at least 6 times higher Urolithin A plasma levels over 24 hours (area under the curve) than 8 ounces (240ml) of pomegranate juice in a randomized human clinical trial.