Athletes running on a running track


Cutting edge research at American Society of Sports Medicine

Published by Jennifer Scheinman
Athletes running on a running track

The American College of Sports Medicine (ACSM) is the leader in training sports professionals around the world. From educating personal trainers to physicians, they are dedicated to helping drive forward advances in exercise science and sports medicine to help both athletes and the public lead healthier lives through physical activity.

Having the opportunity to speak at their annual conference is quite an honor, and we were lucky enough to have three amazing speakers share details from exciting new research being conducted with Mitopure.

Introduction to Mitopure

Our first speaker was Chief Medical Officer of Amazentis, Dr. Anurag Singh, MD, PhD. Dr. Singh introduced the audience to Urolithin A, Mitopure, and some of the compelling research that has occurred over the past decade. He helped the audience to understand how the novel compound Urolithin A works in supporting mitophagy, and it’s potential to greatly impact muscular health. He highlighted the recently published research that demonstrated Mitopure’s ability to improve muscular health in older adults.

If Urolithin A can be so impactful in this population, what could it do for patients in rehabilitation settings or for elite athletes? The next two presenters are hoping to find that out.

Urolithin A interventions for Improving Mitochondrial Health

Mitopure for Rehabilitation

Dr. Stuart Philips spoke next, sharing the important work he is doing to investigate the use of Mitopure in disuse events. A disuse event is when an injury, illness, or surgery requires extended bed rest. In older adults, this convalescent period can lead to a downward trajectory of muscle loss, with the potential to exacerbate the risk of sarcopenia and frailty. Dr. Philips and his team at McMaster University’s Exercise Metabolism Research Group are studying the use of Mitopure in models of disuse to see the ability of Urolithin A to prevent or slow down the degree of muscle wasting.

Prof. Stuart Phillips, PhD: Mitochondrial Health: A key to Aging & Recovering Well (long version)

Mitopure in Elite Athletes

The talk concluded with Professor Louise Burke, researcher and sports dietitian of the Australian Catholic University and Dr. Emily Werner, PhD, RD, LDN, sports dietitian for the NBA’s Philadelphia 76ers. Drs. Burke and Werner shared insights from the application of Mitopure within elite athlete communities, including the initial findings from Dr. Burke’s Enduro study. This trial is examining the impact Mitopure had on elite runners, both in terms of sports performance and biomarkers of muscle and mitochondrial health. While the data collection and analysis is still underway, the results look promising for Urolithin A’s ability to improve exercise performance and cellular measurements of strength and endurance.

Role of Mitochondria in Sports Performance

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These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease. References: *Nutrition studies: 500mg Mitopure® have been shown to (1) induce gene expression related to mitochondria function and metabolism and (2) increase the strength of the hamstring leg muscle in measures of knee extension and flexion in overweight 40-65 year olds. Data from two randomized double-blind placebo-controlled human clinical trials. **Nutrition NOURISH Study: 500mg Mitopure® have been shown to deliver at least 6 times higher Urolithin A plasma levels over 24 hours (area under the curve) than 8 ounces (240ml) of pomegranate juice in a randomized human clinical trial.